Effect of 5 - Fluorouracil on “ Primitive ” Hematopoietic Stem Cells That Reconstitute Whole
نویسنده
چکیده
The potential to reconstitute the whole erythropoiesis of a genetically anemic (WB x C57BL/6)F1-W/W (WBB6F1W/WV) mouse for at least 8 weeks was compared between 5-fluorouracil (5FU)-treated and nontreated bone marrow cells. C57BI/6 Pgk 1b/Pgk 1 female mice, in which each stem cell had either A-type or B-type phosphoglycerate kinase (PGK) owing to the random inactivation of one of two X chromosomes. were used as donors. As a marker of the reconstitution. electrophoretic pattern of hemoglobin was used. The concentration of the stem cells that reconstitute the whole erythropoiesis of WBB6F1WIWY mouse was higher in the marrow of donors that had received an injection of 5FU two days previously (two-day
منابع مشابه
Effect of 5 - Fluorouracil on “ Primitive ” Hematopoietic Stem Cells
The potential to reconstitute the whole erythropoiesis of a genetically anemic (WB x C57BL/6)F1-W/W (WBB6F1W/WV) mouse for at least 8 weeks was compared between 5-fluorouracil (5FU)-treated and nontreated bone marrow cells. C57BI/6 Pgk 1b/Pgk 1 female mice, in which each stem cell had either A-type or B-type phosphoglycerate kinase (PGK) owing to the random inactivation of one of two X chromoso...
متن کاملEffect of 5-fluorouracil on "primitive" hematopoietic stem cells that reconstitute whole erythropoiesis of genetically anemic W/Wv mice.
The potential to reconstitute the whole erythropoiesis of a genetically anemic (WB X C57BL/6)F1-W/Wv (WBB6F1-W/Wv) mouse for at least 8 weeks was compared between 5-fluorouracil (5FU)-treated and nontreated bone marrow cells. C57BL/6-Pgk-1b/Pgk-1a female mice, in which each stem cell had either A-type or B-type phosphoglycerate kinase (PGK) owing to the random inactivation of one of two X chrom...
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تاریخ انتشار 2005